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Following the recalls of metal-on-metal hip replacements, most of us are aware of the potential hazards related to the implant parts which are constructed of cobalt and chromium. Metal poisoning can occur when the metal components rub against one another, causing tiny metal ions to shear away and enter the surrounding tissues and/or the bloodstream. Many recipients of all-metal hip implants—like the recalled Stryker Rejuvenate and ABGII—have ended up with serious health issues from the toxic effects of cobalt and chromium in the body...
Lawsuits Resulting from Stryker’s Rejuvenate and ABGII Hip Stem Recall to be Transferred to the District of Minnesota’s U.S. District Court...
Januvia is a drug manufactured by Merck & Co. to treat Type 2 diabetes, gaining FDA approval in 2006. Januvia contains sitagliptin which inhibits the DPP-4 enzymes in the body, destroying glucagon-like peptide-1 which reduces blood glucose levels. Following a meal, incretin hormones are released from the intestine; these hormone levels are then increased in the bloodstream in patients taking Januvia. When the active ingredient found in Januvia blocks DPP-4, the body can better handle glucose levels, increasing the amount of insulin the pancreas produces when excessive blood sugar demand such an increase. During times when the body does not need the excess liver sugars, the DPP-4 will also lower those sugars. When combined with diet and exercise Januvia can significantly improve blood glucose levels in those with Type 2 diabetes.
Although diabetics do have a greater overall risk of developing pancreatitis, the latest studies seem to support the fact that the DPP-4 Inhibitor Januvia, a drug used to treat Type 2 diabetes, may significantly increase the risk of pancreatitis and pancreatic cancer among users. The pancreas is a gland located behind the stomach with a function of secreting digestive enzymes into the intestine to aid digestion. The pancreas also releases insulin and glucagon into the bloodstream with a goal of regulating the metabolism of blood glucose.
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